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Anti -TDP1 Rabbit pAb

價格: 在線咨詢
貨號:
KT012108
產品規格:
100 μL
Applications:
WB
Species:
MR
購買數量:
立即詢價 在線咨詢 400-1016-218
產品詳情 操作說明 注意事項

Product Information


Description

TDP1 rabbit polyclonal antibody

Protein full name

Tyrosyl-DNA phosphodiesterase 1

Synonyms

Tyr-DNA phosphodiesterase 1, Protein expressed in male leptotene and zygotene spermatocytes 501, MLZ-501, Tdp1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse TDP1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

69 kDa

Observed MW.

69 kDa

Uniprot ID

Q8BJ37, Q4G056




Applications


Applications

Species

Dilution

Positive Sample

WB

Mouse, Rat

1: 500-1: 1000

stomach, liver, kidney




Background


The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1).




Images


Picture 1.png

Western blot analysis of TDP1 (GB111302) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


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