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Anti -GABA A Receptor alpha 1 Rabbit pAb

價格：在線咨詢

貨號：

KT011495

產品規格：

100 μL

Applications：

IHC/IF

Species：

H,M,R

品牌：

萬物

購買數量：

立即詢價在線咨詢 400-1016-218

產品詳情操作說明注意事項

Product Information

Description	GABA A Receptor alpha 1 rabbit polyclonal antibody
Protein full name	Gamma-aminobutyric acid receptor subunit alpha-1
Synonyms	Gabra1, GABRA1, ECA4, EIEE19, EJM, EJM5, gamma-aminobutyric acid type A receptor alpha1 subunit, GABA A Receptor alpha 1
Immunogen	KLH conjugated Synthetic peptide corresponding to Mouse GABA A Receptor alpha 1
Isotype	IgG
Purity	Affinity purification
Subcellular location	Membrane, Secreted
Uniprot ID	P62812

Applications

Applications	Species	Dilution	Positive Sample
IHC/IF	Human, Mouse, Rat	1: 300-1: 1500	brain, cerebellum, glioblastoma multiforme

Background

Gamma-aminobutyric acid receptor subunit alpha-1 is a protein that in humans is encoded by the GABRA1 gene. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. The GABRA1 receptor is the specific target of the z-drug class of nonbenzodiazepine hypnotic agents and is responsible for their hypnotic and hallucinogenic effects.

Images

	Immunohistochemistry of paraffin embedded human brain using GABRA1 (GB11716) at dilution of 1:600
	Immunohistochemistry of paraffin embedded mouse brain using GABRA1 (GB11716) at dilution of 1:600
	Immunohistochemistry of paraffin embedded rat brain using GABRA1 (GB11716) at dilution of 1:600
	Immunohistochemistry of paraffin embedded rat brain using GABRA1 (GB11716) at dilution of 1:600
	Immunohistochemistry of paraffin embedded human glioblastoma multiforme using GABRA1 (GB11716) at dilution of 1:600
	Immunohistochemistry of paraffin embedded mouse cerebellum using GABRA1 (GB11716) at dilution of 1:600
	Immunohistochemistry of paraffin embedded rat cerebellum using GABRA1 (GB11716) at dilution of 1:600

Storage

Storage	Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer	PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .

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