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產品詳情
操作說明
注意事項
Product Information
| Description | CD8 rabbit monoclonal |
| Protein full name | T-cell surface glycoprotein CD8 alpha chain |
| Synonyms | CD8A, CD8, Leu2, MAL, p32,CD8a molecule, CD8 alpha |
| Immunogen | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp42 of mouse CD8α protein |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Cell membrane, Secreted |
| Uniprot ID | P01731, P07725 |
Applications
| Applications | Species | Dilution | Positive Tissue |
| IHC | Mouse | 1: 200-1: 800 | tonsil |
Background
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene
Images
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer .
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合肥萬物生物科技有限公司
客服熱線：400-1016-218
QQ：355185756
地址：安徽省合肥市高新區黃山路602號合肥國家大學科技園A401室